there are a lot of games coming out but the biggest ones to mention are
New Super Mario Brothers Wii 11-15-09
Call of Duty Modern Warfare 2 11-10-09
Call of Duty Modern Warfare reflex (Wii version) 11-10-09
Assassins Creed 2 11-17-09
Force Unleashed Ultimate Sith Edition 11-3-09
Left 4 Dead 2 11-17-09
Feel free to add more if you would like these are the top ones i keep hearing about.